ZANESVILLE, Ohio (AP) — Sheriff's deputies shot nearly 50 wild animals — including 18 rare Bengal tigers and 17 lions — in a big-game hunt across the state's countryside Wednesday after the owner of an exotic-animal park threw their cages open and committed suicide in what may have been one last act of spite against his neighbors and police.

As homeowners nervously hid indoors, officers armed with high-powered rifles and shoot-to-kill orders fanned out through fields and woods to hunt down 56 animals that had been turned loose from the Muskingum County Animal Farm by owner Terry Thompson before he shot himself to death Tuesday.

After an all-night hunt that extended into Wednesday afternoon, 48 animals were killed. Six others — three leopards, a grizzly bear and two monkeys — were captured and taken to the Columbus Zoo. A wolf was later found dead, leaving a monkey as the only animal still on the loose.

Those destroyed included six black bears, two grizzlies, a wolf, a baboon and three mountain lions. Dead animals were being buried on Thompson's farm, officials said.

"It's like Noah's Ark wrecking right here in Zanesville, Ohio," lamented Jack Hanna, TV personality and former director of the Columbus Zoo.

Hanna defended the sheriff's decision to kill the animals but said the deaths of the Bengal tigers were especially tragic. There are only about 1,400 of the endangered cats left in the world, he said.

"When I heard 18, I was still in disbelief," he said. "The most magnificent creature in the entire world, the tiger is."

As the hunt dragged on outside of Zanesville, population 25,000, schools closed in the mostly rural area of farms and widely spaced homes 55 miles east of Columbus. Parents were warned to keep children and pets indoors. And flashing signs along highways told motorists, "Caution exotic animals" and "Stay in vehicle."

Officers were ordered to kill the animals instead of trying to bring them down with tranquilizers for fear that those hit with darts would escape in the darkness before they dropped and would later regain consciousness.

"These animals were on the move, they were showing aggressive behavior," Sheriff Matt Lutz said. "Once the nightfall hit, our biggest concern was having these animals roaming."

The sheriff would not speculate why Thompson killed himself and why he left open the cages and fences at his 73-acre preserve, dooming the animals he seemed to love so much.

Thompson, 62, had had repeated run-ins with the law and his neighbors. Lutz said that the sheriff's office had received numerous complaints since 2004 about animals escaping onto neighbors' property. The sheriff's office also said that Thompson had been charged over the years with animal cruelty, animal neglect and allowing animals to roam.

He had gotten out of federal prison just last month after serving a year for possessing unregistered guns.

John Ellenberger, a neighbor, speculated that Thompson freed the animals to get back at neighbors and police. "Nobody much cared for him," Ellenberger said.

Angie McElfresh, who lives in an apartment near the farm and hunkered down with her family in fear, said "it could have been an 'f-you' to everybody around him."

Thompson had rescued some of the animals at his preserve and purchased many others, said Columbus Zoo spokeswoman Patty Peters.

It was not immediately clear how Thompson managed to support the preserve and for what purpose it was operated, since it was not open to the public. But Thompson had appeared on the "Rachael Ray Show" in 2008 as an animal handler for a zoologist guest, said show spokeswoman Lauren Nowell.

The sheriff's office started getting calls Tuesday evening that wild animals were loose just west of Zanesville. Deputies went to the animal preserve and found Thompson dead and all the cages open. Several aggressive animals were near his body and had to be shot, the sheriff said.

Sheriff's Deputy Jonathan Merry was among the first to respond Tuesday. He said he shot a number of animals, including a gray wolf and a black bear. He said the bear charged him and he fired his pistol, killing it with one shot when it was about 7 feet away.

"All these animals have the ability to take a human out in the length of a second," said Merry, who called himself an animal lover but said he knew he was protecting the community.

"What a tragedy," said Barb Wolfe, a veterinarian with The Wilds, a nearby zoo-sponsored wild animal preserve. She said she managed to hit a tiger with a tranquilizer dart, but the animal charged toward her and then turned and began to flee before the drug could take effect, and deputies shot the big cat.

At an afternoon news conference, the sheriff said that the danger had passed and that people could move around freely again, but that the monkey would probably be shot because it was believed to be carrying a herpes disease.

"It was like a war zone with all the shooting and so forth with the animals," said Sam Kopchak, who was outside Tuesday afternoon when he saw Thompson's horses acting up. Kopchak said he turned and saw a male lion lying down on the other side of a fence.

"The fence is not going to be a fence that's going to hold an African lion," Kopchak said.

Danielle Berkheimer said she was nervous as she drove home Tuesday night and afraid to let her two dogs out in the yard.

"When it's 300-pound cats, that's scary," she said. She said it had been odd Tuesday night to see no one out around town, and the signs warning drivers to stay in their cars were "surreal."

Some townspeople were saddened by the deaths. At a nearby Moose Lodge, Bill Weiser said: "It's breaking my heart, them shooting those animals."

Ohio has some of the nation's weakest restrictions on exotic pets and among the highest number of injuries and deaths caused by them. At least nine people have been injured since 2005 and one person was killed, according to Born Free USA, an animal advocacy group.

On Wednesday, the Humane Society of the United States criticized Gov. John Kasich for allowing a statewide ban on the buying and selling of exotic pets to expire in April. The organization urged the state to immediately issue emergency restrictions.

"How many incidents must we catalog before the state takes action to crack down on private ownership of dangerous exotic animals?" Wayne Pacelle, president and CEO, said in a statement.

Kasich said Wednesday during a meeting of Dix Communications editors: "Clearly, we need tougher laws. We haven't had them in this state. Nobody's dealt with this, and we will. And we'll deal with it in a comprehensive way."

Barney Long, an expert at the World Wildlife Fund, noted that tigers in general are endangered. He said there appear to be fewer of them living in the wild than there are in captivity in the U.S. alone. Over the last century, the worldwide population has plunged from about 100,000 in the wild to as few as 3,200, he said.

More than half are Bengal tigers, which live in isolated pockets across Nepal, Bhutan, Myanmar, India and Bangladesh, he said in a telephone interview

"The tragic shooting of 18 tigers in Ohio really highlights what is happening on a daily basis to tigers in the wild throughout Asia," Long added in an email. "Their numbers are being decimated by poaching and habitat loss, and that is the real travesty here."

Posted previously

ZANESVILLE, Ohio — Dozens of animals escaped Tuesday from a wild-animal preserve that houses bears, big cats and other beasts, and the owner later was found dead there, said police, who shot several of the animals and urged nearby residents to stay indoors.

The fences had been left unsecured at the Muskingum County Animal Farm in Zanesville, in east-central Ohio, and the animals' cages were open, police said. They wouldn't say what animals escaped but said the preserve had lions, wolves, tigers, giraffes, camels and bears. They said bears and wolves were among 25 animals that had been shot and killed and there were multiple sightings of exotic animals along a highway.

"These are wild animals that you would see on TV in Africa," Sheriff Matt Lutz warned at a press conference.

He called the escaped animals "mature, very big, aggressive" but said a caretaker told authorities the preserve's 48 animals had been fed on Monday. He said police were patrolling the 40-acre farm and the surrounding areas in cars, not on foot, and were concerned about big cats and bears hiding in the dark and in trees.

"This is a bad situation," Lutz said. "It's been a situation for a long time."

Lutz said his office started getting phone calls at about 5:30 p.m. that wild animals were loose just west of Zanesville on a road that runs under Interstate 70.

He said four deputies with assault rifles in a pickup truck went to the animal farm, where they found the farm's owner, Terry Thompson, dead and all the animal cage doors open. He didn't say how Thompson died.

The deputies, who saw many animals standing outside their cages and others that had escaped past the fencing surrounding the property, began shooting them. They said there had been no reports of injuries among the public.

Staffers from the Columbus Zoo went to the scene, hoping to tranquilize and capture the animals.

Lutz said people should stay indoors and he might ask for local schools to close Wednesday. He said his main concern was protecting the public.

"Any kind of cat species or bear species is what we are concerned about," Lutz said. "We don't know how much of a head start these animals have on us."

A spokeswoman for the Ohio Department of Natural Resources, which usually handles native wildlife, such as deer, said state Division of Wildlife officers were helping the sheriff's office cope with the exotic animals.

"This is, I would say, unique," spokeswoman Laura Jones said.

In the summer of 2010, an animal caretaker was killed by a bear at a property in Cleveland. The caretaker had opened the bear's cage at exotic-animal keeper Sam Mazzola's property for a routine feeding.

Though animal-rights activists had wanted Mazzola charged with reckless homicide, the caretaker's death was ruled a workplace accident. The bear was later destroyed.

This summer, Mazzola was found dead on a water bed, wearing a mask and with his arms and legs restrained, at his home in Columbia Township, about 15 miles southwest of Cleveland.